The National Commission for Disability in Indonesia has a very strategic role. The presence of the National Commission for Disability is expected to be an important milestone in accelerating the implementation of Indonesia's grand vision for persons with disabilities. The establishment of the National Commission for Disability is a positive first step towards equality of persons with disabilities to create an inclusive, disability-friendly Indonesia environment. In connection with the very strategic role carried out by the National Commission for Disability, it is interesting to investigate further what and how exactly is the position, duties and functions of the National Commission for Disability, which has just been formed in Indonesia since December 1, 2021. With a normative juridical research method, which is descriptive qualitative research, by examining secondary data obtained through Presidential Regulation of the Republic of Indonesia Number 68 of 2020 concerning the National Commission on Disability and other related regulations that are relevant to the position, duties, and functions of the National Commission on Disability. The results of this study indicate that the position of the National Commission for Disability in Indonesia based on Presidential Regulation Number 68 of 2020 is under and responsible to the President. However, the position of the secretariat of the National Commission for Disability is in the work unit in the ministry that carries out government affairs in the social sector. Meanwhile, the duties and functions of the National Commission for Disability in Indonesia: “have the task of monitoring, evaluating, and advocating the implementation of respect, protection, and fulfillment of the rights of persons with disabilities and functions in the preparation of the National Commission for Disability activity plans in an effort to respect, protect, and fulfill the rights of persons with disabilities; monitoring and evaluating the implementation of respect, protection, and fulfillment of the rights of persons with disabilities; advocating the implementation of respect, protection, and fulfillment of the rights of persons with disabilities; and implementation of cooperation in handling persons with disabilities with relevant stakeholders.” Further provisions regarding the implementation of the duties and functions of the National Commission for Disability will be further regulated by a Regulation of the National Commission for Disability.